Searchable abstracts of presentations at key conferences in endocrinology

ea0019p133 | Diabetes, Metabolism and Cardiovascular | SFEBES2009

Adrenal hypertrophy occurs in concert with insulin resistance following high fat feeding of two different strains of rat

McNeilly A , Williamson R , Balfour D , Sutherland C , Stewart C

The incidence of type 2 diabetes (T2DM) has doubled over the past decade. Obesity induced insulin resistance is associated with T2DM and the metabolic syndrome (including hypertension, and dyslipidemia). Diets high in saturated fat are largely to blame for the current obesity epidemic. High-fat feeding of animals increases circulating corticosterone levels, in addition to changes in glucose homeostasis. The relationship between insulin sensitivity and abnormal hypothalamic&#15...